TopGLP1

GLP-1 medications

Every major GLP-1 drug, explained plainly. Tap any medication for a full guide to how it works, how it's dosed, what results to expect, side effects, and what it costs.

Semaglutide

FDA-approved

GLP-1 receptor agonist · Injection or oral · Sold as Ozempic, Wegovy, Rybelsus

The most widely prescribed GLP-1 — sold as Wegovy for weight loss, Ozempic for type 2 diabetes, and Rybelsus as a daily pill.

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Tirzepatide

FDA-approved

Dual GIP/GLP-1 receptor agonist · Subcutaneous injection · Sold as Mounjaro, Zepbound

A dual-hormone injection (Zepbound for weight loss, Mounjaro for diabetes) that has produced the largest average weight loss of any approved GLP-1-class drug so far.

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Retatrutide

Investigational (not yet FDA-approved)

Triple GIP/GLP-1/glucagon receptor agonist · Subcutaneous injection · Sold as (no brand name yet)

An experimental “triple agonist” that produced the largest weight loss seen in trials so far — but it is not yet approved and not legally available.

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Liraglutide

FDA-approved

GLP-1 receptor agonist · Subcutaneous injection · Sold as Saxenda, Victoza

The original once-daily GLP-1 (Saxenda for weight loss, Victoza for diabetes) — now largely superseded by weekly drugs but still relevant, including as a generic.

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Compounded GLP-1

Compounded (not FDA-approved as a finished product)

Pharmacy-compounded semaglutide / tirzepatide · Subcutaneous injection · Sold as Compounded semaglutide, Compounded tirzepatide

Lower-cost versions of semaglutide or tirzepatide mixed by compounding pharmacies — the reason telehealth GLP-1 can cost a fraction of the branded price, with important caveats.

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