Top GLP-1Independent GLP-1 reviews & research

An independent GLP-1 publication

The clear, honest guide to GLP-1 medications

Semaglutide, tirzepatide and retatrutide — how they work, what they really cost, who to get them from, and how to stay safe. Researched against primary sources. No hype, no jargon, no pressure.

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23
programs independently scored
250+
head-to-head comparisons
15
guides & explainers
Every clinical figure cited to NEJM & the FDA Independent — our rankings aren't for sale Written by people, reviewed against primary sources

At the pharmacy

$1,349/mo

Cheapest verified online

from $69/mo

Find your match in 7 questions See cheapest options

Science first

We lead with how the drugs actually work — mechanism, dosing and evidence before any recommendation.

Straight about cost

Branded list prices, compounded pricing, and how insurance really behaves for weight loss vs diabetes.

Honest about risk

Real side effects, real warning signs, and who shouldn't take these medications.

The GLP-1 medications

Deep-dives on each drug — brands, dosing, results, side effects and cost.

FDA-approved

SemaglutideOzempic, Wegovy

The most widely prescribed GLP-1 — sold as Wegovy for weight loss, Ozempic for type 2 diabetes, and Rybelsus as a daily pill.

Read the guide
FDA-approved

TirzepatideMounjaro, Zepbound

A dual-hormone injection (Zepbound for weight loss, Mounjaro for diabetes) that has produced the largest average weight loss of any approved GLP-1-class drug so far.

Read the guide
Investigational (not yet FDA-approved)

Retatrutide(no brand name yet)

An experimental “triple agonist” that produced the largest weight loss seen in trials so far — but it is not yet approved and not legally available.

Read the guide
FDA-approved

LiraglutideSaxenda, Victoza

The original once-daily GLP-1 (Saxenda for weight loss, Victoza for diabetes) — now largely superseded by weekly drugs but still relevant, including as a generic.

Read the guide

Which drug is right for you?

Cited head-to-head comparisons of the medications themselves.

Semaglutide vs Tirzepatide Ozempic vs Wegovy Zepbound vs Wegovy Mounjaro vs Ozempic Semaglutide vs Liraglutide Tirzepatide vs Retatrutide

Start with the essentials

The questions almost everyone has before and during treatment.

Basics

How GLP-1 Medications Actually Work

7 min readSafety

GLP-1 Side Effects and How to Manage Them

8 min readCost

GLP-1 Cost and Insurance: What You'll Actually Pay

7 min readResults

GLP-1 Results Timeline: What to Expect Month by Month

6 min read
Browse all guides

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Am I Eligible? (BMI Checker)

See if you likely meet the clinical criteria in 30 seconds.

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Head-to-head comparisons

No scoreboard — we match each program to your priority (price, brand access, shipping, coaching).

Embody vs Ro

Embody's flat-price compounded GLP-1 versus Ro's branded, insurance-friendly access. A cash-price vs FDA-approved decision, broken down by real cost.

Embody vs altRx

The two lowest-priced compounded GLP-1 programs, head to head — with the actual monthly numbers, formulations and trade-offs laid out.

altRx vs Ro

altRx's low-cost compounded (plus brand) program versus Ro's established branded, insurance-first platform — compared on cost, product and support.

Embody vs TrimRX

Flat, transparent compounded pricing versus a guidance-heavy compounded program — compared on price clarity, support and credentials.

Where to get GLP-1 treatment

If you've decided to pursue treatment, these are the telehealth programs we rate highest for GLP-1 access, pricing and clinical support.

Our #1 pick
1
embody logo

Exceptional

9.9out of 10

Compounded GLP-1 from $69/month, shipped in 1–2 days

Compounded LegitScript-certified Free shipping

Treatments offered

Semaglutide · Tirzepatide

Starting price

$69/mo (compounded semaglutide)

*Compounded medications are not FDA-approved.

  • Semaglutide $69/mo, tirzepatide $119/mo — flat pricing
  • Free 1–2 day shipping, no insurance required
  • Licensed doctors, LegitScript-certified, 503A pharmacies
Visit embody Read full review
3.8 / 5Trustpilot(9,604)

Visit official site · we may earn a commission

Flat-priced compounded semaglutide and tirzepatide with fast shipping.

Read full embody review
2
altRx logo

Excellent

9.6out of 10

The most affordable GLP-1 program, from $89/month

Brand + compounded

Treatments offered

Semaglutide · Tirzepatide

Starting price

$89/mo (compounded semaglutide)

  • Compounded GLP-1 from $89/mo, GLP-1 + GIP from $149/mo
  • Brand-name options too — Zepbound and Wegovy
  • No insurance required; Buy Now, Pay Later available
Visit altRx Read full review

Visit official site · we may earn a commission

Compounded semaglutide and tirzepatide, plus brand-name Zepbound and Wegovy.

Read full altRx review
3
Ro logo

Excellent

9.5out of 10

Simple online GLP-1 care with brand-name access

Brand-name

Treatments offered

Semaglutide · Tirzepatide

Starting price

Membership + medication (insurance-dependent)

  • Licensed providers review every treatment plan
  • Help navigating branded GLP-1 access and insurance
  • Convenient online follow-ups and support
Visit Ro Read full review
3.9 / 5Trustpilot(7,105)

Visit official site · we may earn a commission

Clinician-reviewed access to branded GLP-1 medications and insurance coordination.

Read full Ro review
See all 23 programs, ranked

Find your GLP-1 path

Everything on Top GLP-1, organized by what you’re trying to figure out — the medications, how they compare, what treatment costs, who to get it from, and how to stay safe.

Questions readers ask most

Compounded semaglutide is the cheapest route — our top pick Embody offers it at a flat $69/month, versus $1,000+/month for branded at the pharmacy. See our cheapest-GLP-1 ranking for the full list.

Why trust Top GLP-1?

Top GLP-1 exists to be the clearest GLP-1 explainer on the web. We're upfront that we earn affiliate commissions from some providers — but our medication guides are written to inform, not to sell, and we'll happily tell you when a drug isn't right, when a product isn't legal, or when the honest answer is "talk to your doctor."

Read our editorial approach