Top GLP-1Independent GLP-1 reviews & research

HealthRx vs SHED

HealthRx vs SHED for GLP-1 in 2026 — pricing, medications, shipping and credentials compared side by side.

TGBy the Top GLP-1 Editorial Team· Reviewed 2026-10-05· Cites FDA & NEJM· Not medical advice
21 programs compared Independent — rankings aren't for saleHow we rank →

Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.

Our top choice

HealthRx is our pick for most people here — healthRx is our pick in this matchup — overnight cold-chain shipping and a low semaglutide price. Consider SHED instead if its strength — a strong first-month discount on compounded GLP-1 — matters more to you. The full reasoning, the numbers, and the cases where SHED is the better call are all below.

Check Eligibility: HealthRx
At a glanceHealthRxSHED
Starting price$99/mo (12-month prepaid plan)30% off first month (then plan rate)
MedicationsSemaglutideSemaglutide · Tirzepatide
OfferingCompoundedCompounded
ShippingFree overnight, cold-chainIncluded

Prices are each provider’s published rate at our last check — confirm the final figure at checkout, as offers change. How we rank

HealthRx logo
Licensed telehealth

GLP-1 program from $99/month with overnight delivery

  • Semaglutide from $99/mo on a 12-month prepaid plan
  • Free overnight cold-chain shipping on every plan
  • LegitScript-certified; licensed 503A pharmacies
Visit HealthRx
VS
SHED logo
4.6 / 5(1,134) Licensed telehealth

Science-backed GLP-1, 30% off your first month

  • 30% off your first month
  • Compounded semaglutide and tirzepatide
  • Multiple treatment options
Visit SHED

The full breakdown

HealthRx vs SHED: a closer look at each

HealthRx and SHED are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.

HealthRx logo
OUR PICK
9.0/10#7 of 23· $99/mo (12-month prepaid plan)

Best for: Overnight cold-chain shipping

Choose HealthRx if…

you want HealthRx's edge — overnight cold-chain shipping and a low semaglutide price.

SHED logo
9.2/10#12 of 23· 30% off first month (then plan rate)

Best for: Strong intro discount

Choose SHED if…

you want SHED's edge — a strong first-month discount on compounded GLP-1.

The money

Cost breakdown

The numbers that actually decide it, side by side.

HealthRx
SHED
Starting price$99/mo (12-month prepaid plan)30% off first month (then plan rate)
Semaglutide$99/mo (compounded, 12-month prepaid)Compounded (plan-dependent)
Tirzepatide— (not offered)Compounded (plan-dependent)
OfferingCompoundedCompounded
ShippingFree overnight, cold-chainIncluded
InsuranceCashCash

On price, HealthRx lists $99/mo (compounded, 12-month prepaid) for compounded semaglutide and — (not offered) for tirzepatide, while SHED lists Compounded (plan-dependent) and Compounded (plan-dependent). Where prices are published, HealthRx is the lower-cost option.

Both are cash-pay compounded programs, so the real decision comes down to price, shipping, pharmacy credentials and support rather than the drug itself.

Side by side

Full specs, compared

HealthRx
SHED
Why choose itOvernight cold-chain shipping and a low semaglutide priceA strong first-month discount on compounded GLP-1
Watch out forLowest price needs a 12-month prepay; semaglutide onlyConfirm the ongoing price after the intro month
Starting price$99/mo (12-month prepaid plan)30% off first month (then plan rate)
Compounded semaglutide$99/mo (compounded, 12-month prepaid)Compounded (plan-dependent)
Tirzepatide— (not offered)Compounded (plan-dependent)
GLP-1 + GIP optionNoYes — compounded tirzepatide (GLP-1/GIP)
Offering typeCompoundedCompounded
New-patient offerBest rate via 12-month prepay30% off first month
Billing model12-month prepaid for the lowest rateMonthly plan (intro discount month one)
What's includedClinician consult, Medication, Free overnight cold-chain shippingMedical evaluation, Medication, Shipping
Lab workOnline intakeOnline intake
ShippingFree overnight, cold-chainIncluded
RefillsMonthly shipments on the annual planMonthly refills
StatesMost US statesMost US states
Pharmacy503A pharmacies; LegitScript-certifiedUS compounding pharmacies
CliniciansUS-licensed cliniciansUS-licensed prescribers
InsuranceCashCash
ConsultationOnline clinician consultOnline medical intake
Our rating9.0 · Excellent9.2 · Excellent

The medicine

Medications & formulations

  • HealthRx: compounded GLP-1. No
  • SHED: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)

New to the drugs themselves? Read our plain-language guides to semaglutide, tirzepatide, and the new GLP-1 pills.

The trade-offs

Pros & cons

HealthRx logo

Pros

  • Low $99/mo semaglutide on the annual plan
  • Free overnight cold-chain shipping
  • LegitScript-certified; 503A pharmacies

Cons

  • Best price requires a 12-month prepay
  • Semaglutide only — no tirzepatide
SHED logo

Pros

  • Solid 30%-off intro offer
  • Both semaglutide and tirzepatide
  • Straightforward online process

Cons

  • Ongoing price after intro month less transparent
  • Compounded only

What real SHED customers say

4.6 / 5out of 5

1,134 reviews · checked October 2026

Trustpilot

Verbatim reviews we captured, including every 1-star one.

Sort
Sep 23, 2026

“Gao helped me with several issues very quickly. Very personable too. And I love Shed too”

B

BAG

US

Sep 15, 2026

“Your communications are excellent! Ethan was quick to reply to my request for clarifications. Recommended!”

B

BB

US

Sep 15, 2026

“The app & chat function are a little clunky, but improving. Once you start emailing (not chatting) with a real person, Savannah was the best. Another agent told me I was SOL, but Savannah went a step further and resolved my issue.”

R

R M

US

Sep 11, 2026

“It was a nice personal touch to receive a phone call from a real person instead of a robo call. Thank you for the kind follow up.”

M

Maria M.

US

Sep 2, 2026

“Trinity was absolutely amazing! I accidentally created 2 accounts and thought the issue was resolved from previous interactions with customer service but she assisted me the whole way through and made sure I didn't lose anything that was owed to me and also set up my next follow up appointment. She is fantastic please reward her for this!”

V

Victoria C.

US

Sep 2, 2026

“ShedRx has been awesome! Their service is super-fast, and they even changed my refill date so I wouldn't miss my shot days. Anytime I have an issue, a member support person reaches out right away to help.”

M

Michelle W.

US

“Spoke with Tamika. She was very helpful and informative. She's scheduled a coaching session. Gave me lots of good information.”

C

Cindy C.

US

“Jamika was the representative that called me and she was amazing VERY informative and nice. Asked me if I had any questions made sure I understood the entire process and made me feel very comfortable on my journey with shed!”

J

Jordan R.

US

“Amber was quick to respond to my concern and offered a quick solution! Great customer service!”

J

Joyce H.

US

Sep 14, 2026

“Continued to charge me for months after I stopped the medication. Exclusively AI customer support so don't expect any help. I was told to not expect a refund so I am having to go through my credit card company. Extremely shady company. Edit: in response to their reply, I already contacted support and was told that they will not refund the $1200 they took and delivered nothing.”

J

Justin J.

US

Reviews are individual experiences quoted verbatim from public Trustpilotprofiles, names shortened; any weight-loss result mentioned is one person’s and is not typical — results vary. We don’t edit or curate them to flatter our pick.

Head to head

Where each one wins

We don't tally a single winner — that hides the trade-offs. Here's who leads on each dimension, and why.

Semaglutide price
HealthRx

HealthRx: $99/mo (compounded, 12-month prepaid). SHED: Compounded (plan-dependent).

Medication range
SHED

HealthRx offers compounded; SHED offers compounded.

Shipping
HealthRx

HealthRx: Free overnight, cold-chain. SHED: Included.

Pharmacy credentials
HealthRx

HealthRx publicly states LegitScript certification.

Insurance coordination
Toss-up

Both are primarily cash-pay for compounded GLP-1.

Pick fast

Match it to your priority

Find your top priority, see which program we'd point you to.

If your priority is the lowest published price

HealthRxHealthRx lists the lower semaglutide price.

If your priority is the best shipping

HealthRxFaster/cheaper shipping.

If your priority is our overall pick

HealthRxovernight cold-chain shipping and a low semaglutide price

Questions

HealthRx vs SHED: common questions

Where prices are published, HealthRx lists the lower semaglutide price ($99/mo (compounded, 12-month prepaid)). Both may run promotions and change pricing, so confirm current rates on each site.

The bottom line

HealthRx is our pick in this matchup — overnight cold-chain shipping and a low semaglutide price. Choose SHED only if its strength (a strong first-month discount on compounded GLP-1) matters more to you than price and our overall rating.

How we compare — and how to read this

We weigh the factors that actually change a patient’s experience: real price (and whether it’s compounded or branded), the medications and formulations on offer, shipping, pharmacy accreditation and the clinician model, insurance stance, and commitment. We name a top pick for most people, then lay the trade-offs out in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and moves often — and compounded-drug availability shifts with FDA shortage status — so confirm the current details on the provider’s own site before enrolling. Affiliate relationships never change a program’s placement. This page is educational, not medical advice; see our disclaimer.

Is HealthRx legit? Read the full reviewIs SHED legit? Read the full review