TopGLP1

Ro vs SHED

Ro and SHED are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.

Last reviewed 2026-09-01 · Pricing is provider-reported and changes often — confirm current rates on each provider's site. We may earn a commission.

Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.

Our pick
Ro logo

Ro is our pick in this matchup — established platform for FDA-approved branded GLP-1 with insurance help. Consider SHED instead if its strength — a strong first-month discount on compounded GLP-1 — matters more to you.

View Plan: Ro
Ro logo
OUR PICK

Choose Ro if…

you want Ro's edge — established platform for FDA-approved branded GLP-1 with insurance help.

SHED logo

Choose SHED if…

you want SHED's edge — a strong first-month discount on compounded GLP-1.

Cost breakdown

The numbers that actually decide it, side by side.

Ro logo
Ro
SHED logo
SHED
Starting priceMembership + medication (insurance-dependent)30% off first month (then plan rate)
SemaglutideBrand Wegovy / Ozempic (price depends on insurance)Compounded (plan-dependent)
TirzepatideBrand Zepbound / Mounjaro (price depends on insurance)Compounded (plan-dependent)
OfferingBrandedCompounded
ShippingVia partner/retail pharmacyIncluded
InsuranceWorks with insuranceCash

On price, Ro lists Brand Wegovy / Ozempic (price depends on insurance) for compounded semaglutide and Brand Zepbound / Mounjaro (price depends on insurance) for tirzepatide, while SHED lists Compounded (plan-dependent) and Compounded (plan-dependent). Where prices are published, Ro is the lower-cost option.

The two differ on branded vs compounded, so your insurance situation usually decides it: a covered branded prescription can beat cash compounding, but without coverage compounded is far cheaper.

Full specs, side by side

Ro logo
Ro
SHED logo
SHED
Starting priceMembership + medication (insurance-dependent)30% off first month (then plan rate)
Compounded semaglutideBrand Wegovy / Ozempic (price depends on insurance)Compounded (plan-dependent)
TirzepatideBrand Zepbound / Mounjaro (price depends on insurance)Compounded (plan-dependent)
GLP-1 + GIP optionYes — brand tirzepatide (Zepbound/Mounjaro)Yes — compounded tirzepatide (GLP-1/GIP)
Offering typeBrandedCompounded
New-patient offerVaries by promotion30% off first month
Billing modelMembership plus medication costMonthly plan (intro discount month one)
What's includedClinician review, Ongoing support, Insurance navigationMedical evaluation, Medication, Shipping
Lab workMay be required depending on planOnline intake
ShippingVia partner/retail pharmacyIncluded
RefillsPer prescriptionMonthly refills
StatesNationwideMost US states
PharmacyLicensed retail/mail pharmacies (FDA-approved branded drugs)US compounding pharmacies
CliniciansUS-licensed cliniciansUS-licensed prescribers
InsuranceWorks with insuranceCash
ConsultationClinician-reviewed treatment planOnline medical intake
Our rating9.5 · Excellent9.2 · Excellent

Medications & formulations

  • Ro: branded GLP-1. Yes — brand tirzepatide (Zepbound/Mounjaro)
  • SHED: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)

New to the drugs themselves? Read our plain-language guides to semaglutide and tirzepatide.

Pros & cons

Ro logo

Pros

  • Access to FDA-approved branded GLP-1 (Wegovy, Zepbound, Ozempic, Mounjaro)
  • Insurance coordination and prior-auth help
  • Large, established telehealth platform
  • Clinician review on every plan

Cons

  • Can be expensive without insurance coverage
  • Membership fee on top of medication
  • Branded supply can be affected by shortages
SHED logo

Pros

  • Solid 30%-off intro offer
  • Both semaglutide and tirzepatide
  • Straightforward online process

Cons

  • Ongoing price after intro month less transparent
  • Compounded only

Where each one has the edge

We don't tally a winner — that hides the trade-offs. Here's who leads on each dimension and why.

Semaglutide price
Toss-up

Neither publishes a flat semaglutide price — confirm both directly.

Medication range
Toss-up

Ro offers branded; SHED offers compounded.

Shipping
Toss-up

Ro: Via partner/retail pharmacy. SHED: Included.

Pharmacy credentials
Toss-up

Comparable pharmacy disclosures.

Insurance coordination
Ro

Ro works with insurance.

Match by your priority

The fastest way to decide: find your top priority, see which program we'd point you to.

If your priority is the lowest published price

RoRo lists the lower semaglutide price.

If your priority is the best shipping

RoFaster/cheaper shipping.

If your priority is our overall pick

Roestablished platform for FDA-approved branded GLP-1 with insurance help

Ro vs SHED: common questions

Where prices are published, Ro lists the lower semaglutide price (Brand Wegovy / Ozempic (price depends on insurance)). Both may run promotions and change pricing, so confirm current rates on each site.

The bottom line

Ro is our pick in this matchup — established platform for FDA-approved branded GLP-1 with insurance help. Choose SHED only if its strength (a strong first-month discount on compounded GLP-1) matters more to you than price and our overall rating.

How we compare — and how to read this

We compare programs on the factors that actually affect a patient: real price (including whether it's compounded or branded), medications and formulations offered, shipping, pharmacy accreditation and clinician model, insurance stance, and commitment. We name a top pick for most people, but we show the trade-offs in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and changes frequently — and compounded-drug availability shifts with FDA shortage status — so always confirm the current details on the provider's own site before enrolling. Affiliate relationships do not change a program's placement. This page is educational and not medical advice; see our disclaimer.