Ro vs Yucca
Ro and Yucca are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.
Last reviewed 2026-09-01 · Pricing is provider-reported and changes often — confirm current rates on each provider's site. We may earn a commission.
Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.
Ro is our pick in this matchup — established platform for FDA-approved branded GLP-1 with insurance help. Consider Yucca instead if its strength — nationwide 50-state licensing with a low entry price — matters more to you.
View Plan: RoChoose Ro if…
you want Ro's edge — established platform for FDA-approved branded GLP-1 with insurance help.
Choose Yucca if…
you want Yucca's edge — nationwide 50-state licensing with a low entry price.
Cost breakdown
The numbers that actually decide it, side by side.
| | |
|---|---|---|
| Starting price | Membership + medication (insurance-dependent) | From $146/mo |
| Semaglutide | Brand Wegovy / Ozempic (price depends on insurance) | Compounded (from ~$146/mo) |
| Tirzepatide | Brand Zepbound / Mounjaro (price depends on insurance) | Compounded (plan-dependent) |
| Offering | Branded | Compounded |
| Shipping | Via partner/retail pharmacy | Free expedited |
| Insurance | Works with insurance | Cash |
On price, Ro lists Brand Wegovy / Ozempic (price depends on insurance) for compounded semaglutide and Brand Zepbound / Mounjaro (price depends on insurance) for tirzepatide, while Yucca lists Compounded (from ~$146/mo) and Compounded (plan-dependent). Where prices are published, Yucca is the lower-cost option.
The two differ on branded vs compounded, so your insurance situation usually decides it: a covered branded prescription can beat cash compounding, but without coverage compounded is far cheaper.
Full specs, side by side
| | |
|---|---|---|
| Starting price | Membership + medication (insurance-dependent) | From $146/mo |
| Compounded semaglutide | Brand Wegovy / Ozempic (price depends on insurance) | Compounded (from ~$146/mo) |
| Tirzepatide | Brand Zepbound / Mounjaro (price depends on insurance) | Compounded (plan-dependent) |
| GLP-1 + GIP option | Yes — brand tirzepatide (Zepbound/Mounjaro) | Yes — compounded tirzepatide (GLP-1/GIP) |
| Offering type | Branded | Compounded |
| New-patient offer | Varies by promotion | Varies |
| Billing model | Membership plus medication cost | Monthly plans |
| What's included | Clinician review, Ongoing support, Insurance navigation | Medical evaluation, Medication, Expedited shipping |
| Lab work | May be required depending on plan | Online intake |
| Shipping | Via partner/retail pharmacy | Free expedited |
| Refills | Per prescription | Monthly refills |
| States | Nationwide | All 50 states |
| Pharmacy | Licensed retail/mail pharmacies (FDA-approved branded drugs) | US compounding pharmacies |
| Clinicians | US-licensed clinicians | US-licensed providers |
| Insurance | Works with insurance | Cash |
| Consultation | Clinician-reviewed treatment plan | Online medical intake |
| Our rating | 9.5 · Excellent | 8.1 · Good |
Medications & formulations
- Ro: branded GLP-1. Yes — brand tirzepatide (Zepbound/Mounjaro)
- Yucca: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)
New to the drugs themselves? Read our plain-language guides to semaglutide and tirzepatide.
Pros & cons
Pros
- Access to FDA-approved branded GLP-1 (Wegovy, Zepbound, Ozempic, Mounjaro)
- Insurance coordination and prior-auth help
- Large, established telehealth platform
- Clinician review on every plan
Cons
- Can be expensive without insurance coverage
- Membership fee on top of medication
- Branded supply can be affected by shortages
Pros
- Available in all 50 states
- Free expedited shipping
- Low entry price
Cons
- Smaller review base
- Compounded only
Where each one has the edge
We don't tally a winner — that hides the trade-offs. Here's who leads on each dimension and why.
Ro: Brand Wegovy / Ozempic (price depends on insurance). Yucca: Compounded (from ~$146/mo).
Ro offers branded; Yucca offers compounded.
Ro: Via partner/retail pharmacy. Yucca: Free expedited.
Comparable pharmacy disclosures.
Ro works with insurance.
Match by your priority
The fastest way to decide: find your top priority, see which program we'd point you to.
If your priority is the lowest published price
If your priority is the best shipping
If your priority is our overall pick
Ro vs Yucca: common questions
The bottom line
Ro is our pick in this matchup — established platform for FDA-approved branded GLP-1 with insurance help. Choose Yucca only if its strength (nationwide 50-state licensing with a low entry price) matters more to you than price and our overall rating.
How we compare — and how to read this
We compare programs on the factors that actually affect a patient: real price (including whether it's compounded or branded), medications and formulations offered, shipping, pharmacy accreditation and clinician model, insurance stance, and commitment. We name a top pick for most people, but we show the trade-offs in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and changes frequently — and compounded-drug availability shifts with FDA shortage status — so always confirm the current details on the provider's own site before enrolling. Affiliate relationships do not change a program's placement. This page is educational and not medical advice; see our disclaimer.