TopGLP1

SHED vs Yucca

SHED and Yucca are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.

Last reviewed 2026-09-01 · Pricing is provider-reported and changes often — confirm current rates on each provider's site. We may earn a commission.

Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.

Our pick
SHED logo

SHED is our pick in this matchup — a strong first-month discount on compounded GLP-1. Consider Yucca instead if its strength — nationwide 50-state licensing with a low entry price — matters more to you.

View Plan: SHED
SHED logo
OUR PICK

Choose SHED if…

you want SHED's edge — a strong first-month discount on compounded GLP-1.

Yucca logo

Choose Yucca if…

you want Yucca's edge — nationwide 50-state licensing with a low entry price.

Cost breakdown

The numbers that actually decide it, side by side.

SHED logo
SHED
Yucca logo
Yucca
Starting price30% off first month (then plan rate)From $146/mo
SemaglutideCompounded (plan-dependent)Compounded (from ~$146/mo)
TirzepatideCompounded (plan-dependent)Compounded (plan-dependent)
OfferingCompoundedCompounded
ShippingIncludedFree expedited
InsuranceCashCash

On price, SHED lists Compounded (plan-dependent) for compounded semaglutide and Compounded (plan-dependent) for tirzepatide, while Yucca lists Compounded (from ~$146/mo) and Compounded (plan-dependent). Where prices are published, Yucca is the lower-cost option.

Both are cash-pay compounded programs, so the real decision comes down to price, shipping, pharmacy credentials and support rather than the drug itself.

Full specs, side by side

SHED logo
SHED
Yucca logo
Yucca
Starting price30% off first month (then plan rate)From $146/mo
Compounded semaglutideCompounded (plan-dependent)Compounded (from ~$146/mo)
TirzepatideCompounded (plan-dependent)Compounded (plan-dependent)
GLP-1 + GIP optionYes — compounded tirzepatide (GLP-1/GIP)Yes — compounded tirzepatide (GLP-1/GIP)
Offering typeCompoundedCompounded
New-patient offer30% off first monthVaries
Billing modelMonthly plan (intro discount month one)Monthly plans
What's includedMedical evaluation, Medication, ShippingMedical evaluation, Medication, Expedited shipping
Lab workOnline intakeOnline intake
ShippingIncludedFree expedited
RefillsMonthly refillsMonthly refills
StatesMost US statesAll 50 states
PharmacyUS compounding pharmaciesUS compounding pharmacies
CliniciansUS-licensed prescribersUS-licensed providers
InsuranceCashCash
ConsultationOnline medical intakeOnline medical intake
Our rating9.2 · Excellent8.1 · Good

Medications & formulations

  • SHED: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)
  • Yucca: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)

New to the drugs themselves? Read our plain-language guides to semaglutide and tirzepatide.

Pros & cons

SHED logo

Pros

  • Solid 30%-off intro offer
  • Both semaglutide and tirzepatide
  • Straightforward online process

Cons

  • Ongoing price after intro month less transparent
  • Compounded only
Yucca logo

Pros

  • Available in all 50 states
  • Free expedited shipping
  • Low entry price

Cons

  • Smaller review base
  • Compounded only

Where each one has the edge

We don't tally a winner — that hides the trade-offs. Here's who leads on each dimension and why.

Semaglutide price
Yucca

SHED: Compounded (plan-dependent). Yucca: Compounded (from ~$146/mo).

Medication range
Toss-up

SHED offers compounded; Yucca offers compounded.

Shipping
Yucca

SHED: Included. Yucca: Free expedited.

Pharmacy credentials
Toss-up

Comparable pharmacy disclosures.

Insurance coordination
Toss-up

Both are primarily cash-pay for compounded GLP-1.

Match by your priority

The fastest way to decide: find your top priority, see which program we'd point you to.

If your priority is the lowest published price

YuccaYucca lists the lower semaglutide price.

If your priority is the best shipping

YuccaFaster/cheaper shipping.

If your priority is our overall pick

SHEDa strong first-month discount on compounded GLP-1

SHED vs Yucca: common questions

Where prices are published, Yucca lists the lower semaglutide price (Compounded (from ~$146/mo)). Both may run promotions and change pricing, so confirm current rates on each site.

The bottom line

SHED is our pick in this matchup — a strong first-month discount on compounded GLP-1. Choose Yucca only if its strength (nationwide 50-state licensing with a low entry price) matters more to you than price and our overall rating.

How we compare — and how to read this

We compare programs on the factors that actually affect a patient: real price (including whether it's compounded or branded), medications and formulations offered, shipping, pharmacy accreditation and clinician model, insurance stance, and commitment. We name a top pick for most people, but we show the trade-offs in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and changes frequently — and compounded-drug availability shifts with FDA shortage status — so always confirm the current details on the provider's own site before enrolling. Affiliate relationships do not change a program's placement. This page is educational and not medical advice; see our disclaimer.