TopGLP1

skinnyRx vs Yucca

skinnyRx and Yucca are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.

Last reviewed 2026-09-01 · Pricing is provider-reported and changes often — confirm current rates on each provider's site. We may earn a commission.

Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.

Our pick
skinnyRx logo

skinnyRx is our pick in this matchup — straightforward physician-prescribed compounded GLP-1. Consider Yucca instead if its strength — nationwide 50-state licensing with a low entry price — matters more to you.

View Plan: skinnyRx
skinnyRx logo
OUR PICK

Choose skinnyRx if…

you want skinnyRx's edge — straightforward physician-prescribed compounded GLP-1.

Yucca logo

Choose Yucca if…

you want Yucca's edge — nationwide 50-state licensing with a low entry price.

Cost breakdown

The numbers that actually decide it, side by side.

skinnyRx logo
skinnyRx
Yucca logo
Yucca
Starting priceVaries (not published as a flat rate)From $146/mo
SemaglutideCompounded (plan-dependent)Compounded (from ~$146/mo)
TirzepatideCompounded (plan-dependent)Compounded (plan-dependent)
OfferingCompoundedCompounded
ShippingNationwide home deliveryFree expedited
InsuranceCashCash

On price, skinnyRx lists Compounded (plan-dependent) for compounded semaglutide and Compounded (plan-dependent) for tirzepatide, while Yucca lists Compounded (from ~$146/mo) and Compounded (plan-dependent). Where prices are published, Yucca is the lower-cost option.

Both are cash-pay compounded programs, so the real decision comes down to price, shipping, pharmacy credentials and support rather than the drug itself.

Full specs, side by side

skinnyRx logo
skinnyRx
Yucca logo
Yucca
Starting priceVaries (not published as a flat rate)From $146/mo
Compounded semaglutideCompounded (plan-dependent)Compounded (from ~$146/mo)
TirzepatideCompounded (plan-dependent)Compounded (plan-dependent)
GLP-1 + GIP optionYes — compounded tirzepatide (GLP-1/GIP)Yes — compounded tirzepatide (GLP-1/GIP)
Offering typeCompoundedCompounded
New-patient offerVariesVaries
Billing modelMonthly plansMonthly plans
What's includedPhysician evaluation, Medication, Home deliveryMedical evaluation, Medication, Expedited shipping
Lab workOnline intakeOnline intake
ShippingNationwide home deliveryFree expedited
RefillsMonthly refillsMonthly refills
StatesNationwideAll 50 states
PharmacyUS compounding pharmaciesUS compounding pharmacies
CliniciansUS-licensed physiciansUS-licensed providers
InsuranceCashCash
ConsultationPhysician-prescribed onlineOnline medical intake
Our rating8.0 · Good8.1 · Good

Medications & formulations

  • skinnyRx: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)
  • Yucca: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)

New to the drugs themselves? Read our plain-language guides to semaglutide and tirzepatide.

Pros & cons

skinnyRx logo

Pros

  • Physician-prescribed compounded GLP-1
  • Both semaglutide and tirzepatide
  • Nationwide home delivery

Cons

  • Fewer published details than top-ranked programs
  • Compounded only
Yucca logo

Pros

  • Available in all 50 states
  • Free expedited shipping
  • Low entry price

Cons

  • Smaller review base
  • Compounded only

Where each one has the edge

We don't tally a winner — that hides the trade-offs. Here's who leads on each dimension and why.

Semaglutide price
Yucca

skinnyRx: Compounded (plan-dependent). Yucca: Compounded (from ~$146/mo).

Medication range
Toss-up

skinnyRx offers compounded; Yucca offers compounded.

Shipping
Yucca

skinnyRx: Nationwide home delivery. Yucca: Free expedited.

Pharmacy credentials
Toss-up

Comparable pharmacy disclosures.

Insurance coordination
Toss-up

Both are primarily cash-pay for compounded GLP-1.

Match by your priority

The fastest way to decide: find your top priority, see which program we'd point you to.

If your priority is the lowest published price

YuccaYucca lists the lower semaglutide price.

If your priority is the best shipping

YuccaFaster/cheaper shipping.

If your priority is our overall pick

skinnyRxstraightforward physician-prescribed compounded GLP-1

skinnyRx vs Yucca: common questions

Where prices are published, Yucca lists the lower semaglutide price (Compounded (from ~$146/mo)). Both may run promotions and change pricing, so confirm current rates on each site.

The bottom line

skinnyRx is our pick in this matchup — straightforward physician-prescribed compounded GLP-1. Choose Yucca only if its strength (nationwide 50-state licensing with a low entry price) matters more to you than price and our overall rating.

How we compare — and how to read this

We compare programs on the factors that actually affect a patient: real price (including whether it's compounded or branded), medications and formulations offered, shipping, pharmacy accreditation and clinician model, insurance stance, and commitment. We name a top pick for most people, but we show the trade-offs in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and changes frequently — and compounded-drug availability shifts with FDA shortage status — so always confirm the current details on the provider's own site before enrolling. Affiliate relationships do not change a program's placement. This page is educational and not medical advice; see our disclaimer.