SynergyRX vs Noom
SynergyRX and Noom are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.
Last reviewed 2026-09-01 · Pricing is provider-reported and changes often — confirm current rates on each provider's site. We may earn a commission.
Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.
SynergyRX is our pick in this matchup — hands-on medical supervision at scale. Consider Noom instead if its strength — the strongest behavior-change program of any GLP-1 option — matters more to you.
View Plan: SynergyRXChoose SynergyRX if…
you want SynergyRX's edge — hands-on medical supervision at scale.
Choose Noom if…
you want Noom's edge — the strongest behavior-change program of any GLP-1 option.
Cost breakdown
The numbers that actually decide it, side by side.
| Starting price | Varies (medically supervised plans) | Membership + medication |
|---|---|---|
| Semaglutide | Compounded (plan-dependent) | Brand / plan-dependent |
| Tirzepatide | Compounded (plan-dependent) | Brand / plan-dependent |
| Offering | Compounded | Branded |
| Shipping | Included | Via pharmacy |
| Insurance | Cash | Varies |
On price, SynergyRX lists Compounded (plan-dependent) for compounded semaglutide and Compounded (plan-dependent) for tirzepatide, while Noom lists Brand / plan-dependent and Brand / plan-dependent. Where prices are published, SynergyRX is the lower-cost option.
The two differ on branded vs compounded, so your insurance situation usually decides it: a covered branded prescription can beat cash compounding, but without coverage compounded is far cheaper.
Full specs, side by side
| Starting price | Varies (medically supervised plans) | Membership + medication |
|---|---|---|
| Compounded semaglutide | Compounded (plan-dependent) | Brand / plan-dependent |
| Tirzepatide | Compounded (plan-dependent) | Brand / plan-dependent |
| GLP-1 + GIP option | Yes — compounded tirzepatide (GLP-1/GIP) | Yes — where prescribed |
| Offering type | Compounded | Branded |
| New-patient offer | Varies | Varies by promotion |
| Billing model | Monthly plans | Membership plus medication cost |
| What's included | Physician supervision, Medication, Shipping | Psychology-based program, Coaching, Medical support |
| Lab work | Online intake | May be required |
| Shipping | Included | Via pharmacy |
| Refills | Monthly refills | Per prescription |
| States | Most US states | Nationwide |
| Pharmacy | US compounding pharmacies | Licensed pharmacies |
| Clinicians | US-licensed physicians | US-licensed clinicians + coaches |
| Insurance | Cash | Varies |
| Consultation | Physician-supervised online | App-based program + medical |
| Our rating | 9.0 · Excellent | 8.8 · Very Good |
Medications & formulations
- SynergyRX: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)
- Noom: branded GLP-1. Yes — where prescribed
New to the drugs themselves? Read our plain-language guides to semaglutide and tirzepatide.
Pros & cons
Pros
- Close medical supervision
- Large, established patient base
- Personalized plans
Cons
- Pricing not published as a flat rate
- Compounded only
Pros
- Best-in-class behavior-change program
- Large, trusted brand
- Medication plus habit coaching
Cons
- Membership on top of medication cost
- Program-first, not lowest-price GLP-1
Where each one has the edge
We don't tally a winner — that hides the trade-offs. Here's who leads on each dimension and why.
Neither publishes a flat semaglutide price — confirm both directly.
SynergyRX offers compounded; Noom offers branded.
SynergyRX: Included. Noom: Via pharmacy.
Comparable pharmacy disclosures.
Both are primarily cash-pay for compounded GLP-1.
Match by your priority
The fastest way to decide: find your top priority, see which program we'd point you to.
If your priority is the lowest published price
If your priority is the best shipping
If your priority is our overall pick
SynergyRX vs Noom: common questions
The bottom line
SynergyRX is our pick in this matchup — hands-on medical supervision at scale. Choose Noom only if its strength (the strongest behavior-change program of any GLP-1 option) matters more to you than price and our overall rating.
How we compare — and how to read this
We compare programs on the factors that actually affect a patient: real price (including whether it's compounded or branded), medications and formulations offered, shipping, pharmacy accreditation and clinician model, insurance stance, and commitment. We name a top pick for most people, but we show the trade-offs in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and changes frequently — and compounded-drug availability shifts with FDA shortage status — so always confirm the current details on the provider's own site before enrolling. Affiliate relationships do not change a program's placement. This page is educational and not medical advice; see our disclaimer.