SynergyRX vs Noom
SynergyRX vs Noom for GLP-1 in 2026 — pricing, medications, shipping and credentials compared side by side.
Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.
Our top choice
9.0/10 vs 8.8/10
SynergyRX is our pick for most people here — synergyRX is our pick in this matchup — hands-on medical supervision at scale. Consider Noom instead if its strength — the strongest behavior-change program of any GLP-1 option — matters more to you. The full reasoning, the numbers, and the cases where Noom is the better call are all below.
View Plan: SynergyRX| At a glance | SynergyRX | Noom |
|---|---|---|
| Starting price | Varies (medically supervised plans) | Membership + medication |
| Medications | Semaglutide · Tirzepatide | Semaglutide · Tirzepatide |
| Offering | Compounded | Branded |
| Shipping | Included | Via pharmacy |
Prices are each provider’s published rate at our last check — confirm the final figure at checkout, as offers change. How we rank
Medically supervised GLP-1, lose 1–2 lbs per week
- Personalized medical supervision
- Trusted by over 50,000 patients
- Featured by leading health publications
Behavior-based weight loss with medical support
- Personalized coaching and psychology-based program
- Multiple medication options
- Builds sustainable habits
The full breakdown
SynergyRX vs Noom: a closer look at each
SynergyRX and Noom are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.
Best for: Hands-on medical supervision
Choose SynergyRX if…
you want SynergyRX's edge — hands-on medical supervision at scale.
Best for: Best behavior-change program
Choose Noom if…
you want Noom's edge — the strongest behavior-change program of any GLP-1 option.
The money
Cost breakdown
The numbers that actually decide it, side by side.
| | |
|---|---|---|
| Starting price | Varies (medically supervised plans) | Membership + medication |
| Semaglutide | Compounded (plan-dependent) | Brand / plan-dependent |
| Tirzepatide | Compounded (plan-dependent) | Brand / plan-dependent |
| Offering | Compounded | Branded |
| Shipping | Included | Via pharmacy |
| Insurance | Cash | Varies |
On price, SynergyRX lists Compounded (plan-dependent) for compounded semaglutide and Compounded (plan-dependent) for tirzepatide, while Noom lists Brand / plan-dependent and Brand / plan-dependent. Where prices are published, SynergyRX is the lower-cost option.
The two differ on branded vs compounded, so your insurance situation usually decides it: a covered branded prescription can beat cash compounding, but without coverage compounded is far cheaper.
Side by side
Full specs, compared
| | |
|---|---|---|
| Why choose it | Hands-on medical supervision at scale | The strongest behavior-change program of any GLP-1 option |
| Watch out for | Entry pricing isn't published as one flat number | You're paying for the program, not the cheapest medication |
| Starting price | Varies (medically supervised plans) | Membership + medication |
| Compounded semaglutide | Compounded (plan-dependent) | Brand / plan-dependent |
| Tirzepatide | Compounded (plan-dependent) | Brand / plan-dependent |
| GLP-1 + GIP option | Yes — compounded tirzepatide (GLP-1/GIP) | Yes — where prescribed |
| Offering type | Compounded | Branded |
| New-patient offer | Varies | Varies by promotion |
| Billing model | Monthly plans | Membership plus medication cost |
| What's included | Physician supervision, Medication, Shipping | Psychology-based program, Coaching, Medical support |
| Lab work | Online intake | May be required |
| Shipping | Included | Via pharmacy |
| Refills | Monthly refills | Per prescription |
| States | Most US states | Nationwide |
| Pharmacy | US compounding pharmacies | Licensed pharmacies |
| Clinicians | US-licensed physicians | US-licensed clinicians + coaches |
| Insurance | Cash | Varies |
| Consultation | Physician-supervised online | App-based program + medical |
| Our rating | 9.0 · Excellent | 8.8 · Very Good |
The medicine
Medications & formulations
- SynergyRX: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)
- Noom: branded GLP-1. Yes — where prescribed
New to the drugs themselves? Read our plain-language guides to semaglutide, tirzepatide, and the new GLP-1 pills.
The trade-offs
Pros & cons
Pros
- Close medical supervision
- Large, established patient base
- Personalized plans
Cons
- Pricing not published as a flat rate
- Compounded only
Pros
- Best-in-class behavior-change program
- Large, trusted brand
- Medication plus habit coaching
Cons
- Membership on top of medication cost
- Program-first, not lowest-price GLP-1
Head to head
Where each one wins
We don't tally a single winner — that hides the trade-offs. Here's who leads on each dimension, and why.
Neither publishes a flat semaglutide price — confirm both directly.
SynergyRX offers compounded; Noom offers branded.
SynergyRX: Included. Noom: Via pharmacy.
Comparable pharmacy disclosures.
Both are primarily cash-pay for compounded GLP-1.
Pick fast
Match it to your priority
Find your top priority, see which program we'd point you to.
If your priority is the lowest published price
If your priority is the best shipping
If your priority is our overall pick
Questions
SynergyRX vs Noom: common questions
The bottom line
SynergyRX is our pick in this matchup — hands-on medical supervision at scale. Choose Noom only if its strength (the strongest behavior-change program of any GLP-1 option) matters more to you than price and our overall rating.
How we compare — and how to read this
We weigh the factors that actually change a patient’s experience: real price (and whether it’s compounded or branded), the medications and formulations on offer, shipping, pharmacy accreditation and the clinician model, insurance stance, and commitment. We name a top pick for most people, then lay the trade-offs out in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and moves often — and compounded-drug availability shifts with FDA shortage status — so confirm the current details on the provider’s own site before enrolling. Affiliate relationships never change a program’s placement. This page is educational, not medical advice; see our disclaimer.