Top GLP-1Independent GLP-1 reviews & research

TrimRX vs Medvi

TrimRX vs Medvi for GLP-1 in 2026 — pricing, medications, shipping and credentials compared side by side.

TGBy the Top GLP-1 Editorial Team· Reviewed 2026-10-05· Cites FDA & NEJM· Not medical advice
21 programs compared Independent — rankings aren't for saleHow we rank →

Educational, not medical advice. This page explains GLP-1 medications in general terms. Only a licensed clinician who knows your history can decide what's right for you.

Our top choice

9.4/10 vs 8.5/10

TrimRX is our pick for most people here — trimRX is our pick in this matchup — ongoing clinical guidance rather than a one-and-done script. Consider Medvi instead if its strength — a simple, no-friction path to compounded GLP-1 — matters more to you. The full reasoning, the numbers, and the cases where Medvi is the better call are all below.

View Plan: TrimRX
At a glanceTrimRXMedvi
Starting priceCompetitive (varies by plan — not a single flat number)Varies by plan
MedicationsSemaglutide · TirzepatideSemaglutide · Tirzepatide
OfferingCompoundedCompounded
ShippingIncludedIncluded

Prices are each provider’s published rate at our last check — confirm the final figure at checkout, as offers change. How we rank

TrimRX logo
3.7 / 5(5,392) Licensed telehealth

Affordable access to GLP-1 programs

  • Competitive monthly pricing
  • Flexible treatment plans available
  • Ongoing clinical guidance included
Visit TrimRX
VS
Medvi logo
4.3 / 5(14,987) Licensed telehealth

Medical weight loss made simple

  • Prescription-based treatment options
  • Provider support throughout
  • Straightforward online enrollment

The full breakdown

TrimRX vs Medvi: a closer look at each

TrimRX and Medvi are both telehealth GLP-1 programs, but they differ on price, medications, shipping and how you pay. Here's the side-by-side, with the numbers, so you can pick the right one.

TrimRX logo
OUR PICK
9.4/10#4 of 23· Competitive (varies by plan — not a single flat number)

Best for: Ongoing clinical guidance

Choose TrimRX if…

you want TrimRX's edge — ongoing clinical guidance rather than a one-and-done script.

Medvi logo
8.5/10#17 of 23· Varies by plan

Best for: Simple, no-friction enrollment

Choose Medvi if…

you want Medvi's edge — a simple, no-friction path to compounded GLP-1.

The money

Cost breakdown

The numbers that actually decide it, side by side.

TrimRX
Medvi
Starting priceCompetitive (varies by plan — not a single flat number)Varies by plan
SemaglutideCompounded (plan-dependent)Compounded (plan-dependent)
TirzepatideCompounded (plan-dependent)Compounded (plan-dependent)
OfferingCompoundedCompounded
ShippingIncludedIncluded
InsuranceCashCash

On price, TrimRX lists Compounded (plan-dependent) for compounded semaglutide and Compounded (plan-dependent) for tirzepatide, while Medvi lists Compounded (plan-dependent) and Compounded (plan-dependent). Where prices are published, TrimRX is the lower-cost option.

Both are cash-pay compounded programs, so the real decision comes down to price, shipping, pharmacy credentials and support rather than the drug itself.

Side by side

Full specs, compared

TrimRX
Medvi
Why choose itOngoing clinical guidance rather than a one-and-done scriptA simple, no-friction path to compounded GLP-1
Watch out forEntry pricing is less transparent upfrontEntry pricing isn't published upfront
Starting priceCompetitive (varies by plan — not a single flat number)Varies by plan
Compounded semaglutideCompounded (plan-dependent)Compounded (plan-dependent)
TirzepatideCompounded (plan-dependent)Compounded (plan-dependent)
GLP-1 + GIP optionYes — compounded tirzepatide (GLP-1/GIP)Yes — compounded tirzepatide (GLP-1/GIP)
Offering typeCompoundedCompounded
New-patient offerVaries by planVaries
Billing modelFlexible monthly plansMonthly plans
What's includedMedical evaluation, Medication, Ongoing clinical guidanceMedical evaluation, Medication, Provider support
Lab workOnline intake; guidance-led follow-upOnline intake
ShippingIncludedIncluded
RefillsMonthly refillsMonthly refills
StatesMost US statesMost US states
PharmacyUS compounding pharmaciesUS compounding pharmacies
CliniciansUS-licensed prescribersUS-licensed prescribers
InsuranceCashCash
ConsultationOnline intake with ongoing clinical guidanceOnline medical intake
Our rating9.4 · Excellent8.5 · Very Good

The medicine

Medications & formulations

  • TrimRX: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)
  • Medvi: compounded GLP-1. Yes — compounded tirzepatide (GLP-1/GIP)

New to the drugs themselves? Read our plain-language guides to semaglutide, tirzepatide, and the new GLP-1 pills.

The trade-offs

Pros & cons

TrimRX logo

Pros

  • Ongoing clinical guidance, not a one-and-done script
  • Both semaglutide and tirzepatide offered
  • Flexible, adjustable plans

Cons

  • Entry pricing not published as a single flat number
  • Compounded only
Medvi logo

Pros

  • Simple enrollment
  • Ongoing provider support
  • Prescription-based

Cons

  • Pricing not published as a flat rate
  • Compounded only

What real TrimRX customers say

3.7 / 5out of 5

5,392 reviews · checked October 2026

Trustpilot

Verbatim reviews we captured, including every 2-star one.

Sort
Sep 24, 2026

“Priced fairly and easy to use”

J

Jerald W.

US

Sep 24, 2026

“Screening was more thorough than I expected and the communication has not dropped off since. Two other places went quiet right after payment.”

J

Jean B.

US

Sep 24, 2026

“Support replies fast and nothing felt rushed, super”

M

Mary O.

US

Sep 23, 2026

“The company I used before charged me every month and never sent anything. Then a separate shipper billed me again for a package that never showed up. I'm still chasing that money and I've mostly given up on it. What's different this time is how many emails TrimRx sends without me asking. Order confirmed, prescription written, label created, out for delivery, four messages in five days.”

N

Narine P.

US

Sep 23, 2026

“The box is labeled plainly, nothing that gives it away on the porch, thanks!!”

N

Nicholas H.

US

Sep 23, 2026

“My old provider was charging me close to double this!”

S

Sharon B.

US

Sep 23, 2026

“Communication has been the strong point”

J

James M.

US

Sep 23, 2026

“The intake was clear, I never had to guess at a question, and getting from submitted to approved took no time at all.”

H

Herminia L.

US

Sep 23, 2026

“Clear pricing, no hand holding needed.”

A

Alain

US

Sep 23, 2026

“Shipping runs two or three days and the box arrives cold.”

J

Jaime D.

US

Aug 3, 2026

“I started my weight loss journey on May 1st. I have lost 41 lbs. It's more than just the weight loss. The things you used to think were fun like gambling, drinking, and smoking no longer are rewarding. Spending time with my grandson now - that's a good time. My mental clarity has so improved. My high blood pressure is gone. I'm happier than I've been in years. The Trizepatide with B12 from TrimRx really works! I've still got another 50 lbs to go. If you're skeptical about GLP-1s, don't be.”

S

Steve T.

US

Jul 28, 2026

“Cynthia reached out not long after I had gone through the online process. She was very kind and helpful and understanding that I was looking to find the best support and costs for my weightloss. Ultimately I decided to fight my Dr, but for those that need good support along the way you cant go wrong using Trim Rx.”

K

Katrina C.

US

Jul 18, 2026

“I opened the first box yesterday, everything was there and properly sealed. A good start.”

L

Lisa C.

US

Jul 18, 2026

“Just took my 3rd injection. Down 4 pounds so far, it's been a good experience.”

N

Nichole Y.

US

Jul 18, 2026

“Payment went through without any problems and the box arrived exactly when they promised. Everything correct.”

J

Jessica J.

US

Jul 18, 2026

“I had a question and they got back to me the same day. Friendly and to the point.”

N

Nadia T.

US

Jul 17, 2026

“The provider went through my health history before approving the prescription. I didn't feel rushed through it.”

A

Alejandro A.

US

Sep 21, 2026

“Whoever was helping me answered my questions and followed up after, and communication has been solid the whole way. My one gripe is it was supposed to arrive in 48 hours and it actually took 5 days.”

M

Michael H.

US

Sep 22, 2026

“The price runs a little high, but if the quality holds I don't mind paying it. Delivery has been great every time and the whole thing is easy to follow. So far it's going well. The only frustrating part is those weeks where the scale just sits, though I knew that would happen.”

T

Tiffany C.

US

Sep 23, 2026

“The tracking date moved twice and the box came three days late, and the cold packs were warm to the touch when I finally opened it.”

H

Holly H.

US

Sep 23, 2026

“The medication was not working for me, so I canceled my prescription but I am still receiving text and emails from Affirm saying they have not received cancellation from trim rx and is trying to continue charging me each month.”

G

George L.

US

Sep 21, 2026

“The onboarding process was fine, telehealth etc. They processed my order AND full payment very quickly. I signed up for a 6-month plan which delivers in two deliveries. First upon approval and second 3 months later. I've not received the second order; which I already paid for, and it's over 30 days late. They do not respond on their website chat or answer the phone when called. I've been trying to contact someone for 10 days. I finally ended up disputing with my CC company.”

K

Karen A.

US

Sep 20, 2026

“This is my first order with TrimRX. I've not even received the order and I'm already having problems. The RX that was sent to my patient portal was not even me. I tried to reach out via chat....nothing. Email? No response. The phone call was automated and someone should be reaching out to me soon. I've yet to hear back. Email codes are not being received by me and the charge on my next bill is double what they'd told me initially. $399 for a month of Tirzepatide? I could purchase Mounjaro for less. In the meantime....rx has been shipped out without anyone contacting me about the incorrect rx information. Very very dissatisfied and will not be ordering from them again. Too much of a hassle.”

M

Mrs V

US

Reviews are individual experiences quoted verbatim from public Trustpilotprofiles, names shortened; any weight-loss result mentioned is one person’s and is not typical — results vary. We don’t edit or curate them to flatter our pick.

What real Medvi customers say

4.3 / 5out of 5

14,987 reviews · checked October 2026

Trustpilot

Verbatim reviews we captured, including every 1-star one.

Sort
Sep 25, 2026

“Very helpful information. Theresa was thoughtful and explained all of her observations.”

E

Eric B.

US

Sep 25, 2026

“Nurse was very informative and pleasant to talk with.”

S

Stephen V.

US

Sep 25, 2026

“This journey has been great . Talking with Jessica certainly has answered my questions and concerns.”

L

Linda H.

US

Sep 24, 2026

“My provider was very helpful. She listened to my concerns and made proper adjustments.”

C

Crystal C.

US

Sep 24, 2026

“Tomica, the company rep was outstanding.”

J

John W.

US

Sep 24, 2026

“I was able to ask any questions, she was very informative.”

M

Maria A.

US

Sep 23, 2026

“MedVi support and their affordable access to these truly life saving medicines is wonderful. I'm beyond grateful.”

K

Kelly G.

US

Sep 23, 2026

“They really care about my needs and goals.”

S

Sandra C.

US

Sep 23, 2026

“The doctor reviewed my history of orders and saw the mistake previously made and said she would correct my prescription order. All was great and can't think of any improvements. The program has been working fantastic for me and highly recommend.”

N

Nan

US

Sep 23, 2026

“That you meet with a real provider or nurse practitioner via video call I think is more important than a phone call. Things are cleared in your visit. Much better. They're always available, easy to make appointments”

M

Michele S.

US

Sep 22, 2026

“Uneventful, went as hoped”

S

Stev H.

US

Sep 22, 2026

“Experience was handled professionally and I was given well informed information on my weight loss medication and journey and what to expect. I was very comfortable knowing I can contact medical personnel at anytime with any questions or concerns. Overall I am very happy”

M

May L.

US

Sep 22, 2026

“The RN was very helpful with my medical questions as well as assuring me that things will be taken care of.”

S

Stephanie N.

US

Sep 22, 2026

“Very helpful and cooperative. I'm very satisfied.”

A

Alfred J.

US

Sep 22, 2026

“Today I had a great follow up, check-in appointment with a nurse practitioner after having a surgical procedure done. We went over expectations, where I met with my dosages, how to continue with my dosages now that I have recovered from surgery. All in all it was a great experience; so far everything has gone really well with this MedVi tirzepatide health adventure I have undertaken.”

J

Jennifer P.

US

Sep 22, 2026

“Helpful and thorough”

T

Tracy H.

US

Sep 22, 2026

“The nurse was very kind, professional and helpful. Thank you and keep up the good work. Unfortunately this company dosage peaks out at 11.125mg unlike some other companies that go to a max dosage of 15mg”

M

Maurice R.

US

Aug 10, 2026

“My provider was very friendly. She answered all my questions very thoughtfully and thoroughly.”

A

Ashley

US

Aug 10, 2026

“Timely and helpful video call resolving my issues.”

S

Scott C.

US

Aug 10, 2026

“The nurse paid close attention to my questions and responded in ways that were very helpful. Great job!”

R

Rena

US

Aug 7, 2026

“Video visit was made very easy and reminders were sent right before my visit”

M

Martin

US

Aug 7, 2026

“The person who helped me listened and helped me with my problems”

R

Richard

US

Aug 7, 2026

“The phone call was very thorough and everything went smoothly”

R

Randy B.

US

Aug 7, 2026

“My experience was highly satisfactory, and all my inquiries were addressed to my complete satisfaction.”

T

Traci F.

US

Aug 7, 2026

“The teams at Medvi always help to assist with my concerns and have been supportive and positive through my weight-loss journey.”

V

Veronica

US

Jul 28, 2026

“She was very professional and considerate. The video call was on time and straightforward.”

G

Greg R.

US

“The personal service”

D

DB

US

“She took her time, answered any questions. Very satisfied thank you”

R

Raymond S.

US

“Friendly professional answered my questions. Thank you!”

l

lisa E.

US

“Professional summary, courtesy, thoroughly recommended and helpful information for my case.”

B

Brian

US

Sep 22, 2026

“Very personal, communicated all needs and supported me with advice”

R

Roxanne C.

US

Sep 21, 2026

“Quick, easy, to the point.”

S

Shawn E.

US

Sep 5, 2026

“Helpful personnel.”

V

Vivian H.

US

Sep 4, 2026

“At first had a hard time canceling my monthly subscription, but they did finally get that taken care of. The product is great, I just didnt need/want a monthly prescription. I wish they had more flexibility in that regard. Maybe an every other month, or just buy as needed.”

C

Chris W.

US

Aug 31, 2026

“MEDVi offers a lot of assistance with the RN, Provider. and Coaching Support - I like that assistance. However, they need to ensure for a solid audio-video connection to see whom you're speaking with (there's too much FRAUD going on today) especially when it comes to your health. It's very important to see and get there credentials/whom you're speaking with about your health - you know, the HIPPA ACT Policy. Otherwise, I really enjoy this Rx, it really curves your appetite. My PRAYER is NO side effects so that I can continue and accomplish my goal. I started this program in March 2026. It cost too much not to receive stellar service.”

A

A Concerned First Time Consume

US

Sep 23, 2026

“Caution is advised. The operational efficiency of this company is significantly lagging, causing an impediment to my regular medication intake schedule. Regrettably, their customer support inadequacies persist, coupled with a lack of responsibility for service deficiencies. In addition, their pricing surpasses that of competitors. It is my recommendation to refrain from engaging with this establishment due to their unreliability in ensuring timely delivery of essential medications for weekly GLP-1 dosages.”

K

Kearsley R.

US

Sep 22, 2026

“For the first 5 months, they were great. Good service. Good communication. Then, all communication stopped: no emails, no text. I called and canceled. But they would not send me a cancellation email. In three additional calls.”

A

Andy W.

US

Sep 16, 2026

“I transitioned to Medvi from another company and have been using GLP-1s for over a year. Medvi didn't review my history and continuously sent me a level 1 prescription when I needed a level 5. It took weeks to get each one resolved, including multiple calls/emails with customer service, and having to explain why I didn't want to pay more money for the "extra prescriptions". I paid for three months, but will not be renewing after these months are over.”

N

N R

US

Sep 11, 2026

“I signed up for medication and was charged without ever having spoken to a medical professional. They ordered medication that was an incorrect dose. I met with their medical provider and she agreed to change to the correct dose. The change was never made. I called numerous times to correct the problem, I was assured that it was corrected. It never was. I called to cancel the order and request a refund. I was told I would have a refund in 5-10 days. I didn't receive confirmation of the refund and was getting notified that the prescription was being processed. I called again and was told to ignore the notification that it was cancelled and I would receive a refund. The order was shipped to me. It is not labeled with the correct dosage and the company is now refusing the refund I was promised. I have been on the phone and in email communication almost daily. DO NOT DO BUSINESS with MEDVI. They are not trustworthy. They will lie to you and refuse to honor their word.”

D

Deborah D.

US

Sep 1, 2026

“Medvi promised GLP 1 medication for $179.00 monthly with a prepaid yearly subscription. Unfortunately the term was not a complete year. After just 11 shipments they renewed my subscription without any advance notice. They did not give me a choice. The amount I was charged previously was $2,148.01. If you divide this amount by 11 it does not come out to $179.00. When I did discover the charge applied to my card, I contacted Medvi that same day to cancel my subscription. They replied that they have cancelled it the following August in 2027. They would not allow me to cancel the current subscription. Not until I filed complaints with the Better Business Bureau, the FTC, and my State Attorney General did they finally refund my subscription. I would not deal with this company. Even though the medication was supposed to be monthly, the dosage that I was prescribed was two injections weekly. The dosage amount and the amount that they sent did not last for 8 injections for the month.”

M

Margaret D.

US

Reviews are individual experiences quoted verbatim from public Trustpilotprofiles, names shortened; any weight-loss result mentioned is one person’s and is not typical — results vary. We don’t edit or curate them to flatter our pick.

Head to head

Where each one wins

We don't tally a single winner — that hides the trade-offs. Here's who leads on each dimension, and why.

Semaglutide price
Toss-up

Neither publishes a flat semaglutide price — confirm both directly.

Medication range
Toss-up

TrimRX offers compounded; Medvi offers compounded.

Shipping
Toss-up

TrimRX: Included. Medvi: Included.

Pharmacy credentials
Toss-up

Comparable pharmacy disclosures.

Insurance coordination
Toss-up

Both are primarily cash-pay for compounded GLP-1.

Pick fast

Match it to your priority

Find your top priority, see which program we'd point you to.

If your priority is the lowest published price

TrimRXTrimRX lists the lower semaglutide price.

If your priority is the best shipping

TrimRXFaster/cheaper shipping.

If your priority is our overall pick

TrimRXongoing clinical guidance rather than a one-and-done script

Questions

TrimRX vs Medvi: common questions

Where prices are published, TrimRX lists the lower semaglutide price (Compounded (plan-dependent)). Both may run promotions and change pricing, so confirm current rates on each site.

The bottom line

TrimRX is our pick in this matchup — ongoing clinical guidance rather than a one-and-done script. Choose Medvi only if its strength (a simple, no-friction path to compounded GLP-1) matters more to you than price and our overall rating.

How we compare — and how to read this

We weigh the factors that actually change a patient’s experience: real price (and whether it’s compounded or branded), the medications and formulations on offer, shipping, pharmacy accreditation and the clinician model, insurance stance, and commitment. We name a top pick for most people, then lay the trade-offs out in full so you can override it when your priorities or insurance point the other way. Pricing is provider-reported and moves often — and compounded-drug availability shifts with FDA shortage status — so confirm the current details on the provider’s own site before enrolling. Affiliate relationships never change a program’s placement. This page is educational, not medical advice; see our disclaimer.

Is TrimRX legit? Read the full reviewIs Medvi legit? Read the full review